David E Jones Selected Research

1'-hydroxyestragole

1/2016

Progenitor-derived hepatocyte-like (B-13/H) cells metabolise 1'-hydroxyestragole to a genotoxic species via a SULT2B1-dependent mechanism.

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David E Jones Research Topics

Disease

24	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2022 - 12/2008
10	Fatigue 01/2022 - 04/2009
9	Multiple Sclerosis 01/2018 - 12/2013
4	Pruritus (Itching) 01/2022 - 08/2016
4	Liver Diseases (Liver Disease) 01/2021 - 01/2014
4	Disease Progression 01/2018 - 01/2014
4	Neoplasms (Cancer) 01/2015 - 01/2014
3	Infections 09/2016 - 07/2014
2	Inflammation (Inflammations) 01/2022 - 10/2014
2	Progressive Multifocal Leukoencephalopathy 01/2021 - 01/2018
2	Fibrosis (Cirrhosis) 10/2017 - 08/2016
1	Intestinal Failure 01/2022
1	Opportunistic Infections (Opportunistic Infection) 01/2021
1	Rare Diseases (Rare Disease) 10/2017
1	Paraneoplastic Syndromes (Paraneoplastic Syndrome) 01/2017
1	Headache (Headaches) 01/2017
1	Cryptococcal Meningitis 09/2016
1	Lymphopenia (Lymphocytopenia) 09/2016
1	Cholangiocarcinoma 01/2016
1	Atrophy 01/2016
1	Chronic Fatigue Syndrome (Myalgic Encephalomyelitis) 01/2015
1	Relapsing-Remitting Multiple Sclerosis 10/2014
1	Virus Diseases (Viral Diseases) 07/2014
1	Bradycardia 07/2014
1	Macular Edema 07/2014
1	Atrioventricular Block 07/2014
1	Ductal Carcinoma 01/2014
1	Adult Form Polyglucosan Body Disease 01/2014
1	Hepatitis 01/2014
1	Stillbirth 01/2014
1	Diabetic Neuropathies (Diabetic Neuropathy) 06/2005
1	Leukemia 08/2003
1	Breast Neoplasms (Breast Cancer) 08/2003

Drug/Important Bio-Agent (IBA)

6	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 05/2018 - 01/2014
3	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 01/2017
3	Rituximab (Mabthera)FDA Link 11/2019 - 08/2015
3	Fingolimod Hydrochloride (FTY720)FDA Link 01/2018 - 07/2014
2	Dimethyl FumarateIBA 01/2021 - 01/2018
2	Ionic LiquidsIBA 01/2021 - 02/2020
2	3- ((((3R,5R)- 3- butyl- 3- ethyl- 7- (methyloxy)- 1,1- dioxido- 5- phenyl- 2,3,4,5- tetrahydro- 1,4- benzothiazepin- 8- yl)methyl)amino)pentanedioic acidIBA 01/2019 - 01/2017
2	bile acid binding proteinsIBA 01/2019 - 01/2017
2	Thioctic Acid (Lipoic Acid)IBA 11/2018 - 12/2008
2	Pyruvate Dehydrogenase Complex (Dehydrogenase Complex, Pyruvate)IBA 11/2018 - 12/2008
2	ocrelizumabIBA 01/2018 - 01/2018
2	Alkaline PhosphataseIBA 01/2018 - 08/2016
2	Pharmaceutical PreparationsIBA 10/2017 - 11/2016
2	obeticholic acidIBA 11/2016 - 08/2016
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 09/2016 - 07/2014
1	seladelparIBA 01/2022
1	SolutionsIBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 05/2021
1	Amino Acids FDA Link 12/2018
1	XenobioticsIBA 11/2018
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 11/2018
1	AntibodiesIBA 11/2018
1	Chemokine CXCL10IBA 05/2018
1	Natalizumab (Tysabri)FDA Link 01/2018
1	Intravenous Immunoglobulins (IVIG)FDA Link 01/2017
1	Quinidine (Chinidin)FDA LinkGeneric 01/2017
1	Antidepressive Agents (Antidepressants)IBA 01/2017
1	Dextromethorphan (Racemethorphan)FDA LinkGeneric 01/2017
1	BilirubinIBA 08/2016
1	estragole (methyl chavicol)IBA 01/2016
1	1'-hydroxyestragoleIBA 01/2016
1	Biological ProductsIBA 01/2015
1	Glucose (Dextrose)FDA LinkGeneric 01/2015
1	PAMAM StarburstIBA 01/2015
1	Alemtuzumab (Campath)FDA Link 10/2014
1	Oligoclonal BandsIBA 01/2014
1	polyglucosanIBA 01/2014
1	Nuclear Antigens (Extractable Nuclear Antigens)IBA 01/2014
1	Dendrimers (Dendrons)IBA 01/2014
1	Environmental Pollutants (Pollutants, Environmental)IBA 01/2014
1	1,4-alpha-Glucan Branching Enzyme (Glycogen Branching Enzyme)IBA 01/2014
1	CytokinesIBA 01/2014
1	ManganeseIBA 04/2009
1	EnzymesIBA 12/2008
1	EpitopesIBA 12/2008
1	AntigensIBA 12/2008
1	Hormones (Hormone)IBA 08/2003

Therapy/Procedure

19	Therapeutics 01/2022 - 11/2010
6	Liver Transplantation 06/2018 - 09/2013
2	Transplantation 01/2014 - 09/2013
1	Home Parenteral Nutrition 01/2022
1	Intravenous Administration 05/2018
1	Exercise Therapy (Therapy, Exercise) 07/2016
1	Aftercare (After-Treatment) 10/2014
1	Drug Therapy (Chemotherapy) 01/2014
1	Glycemic Control 06/2005